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Kansas City Chiefs vs. San Francisco 49ers Prediction, Odds, Moneyline 10/20/2024
Oct 7, 2024; Kansas City, Missouri, USA; Kansas City Chiefs wide receiver Xavier Worthy (1) celebrates with wide receiver JuJu Smith-Schuster (9) and running back Carson Steele (42) after scoring a touchdown against the New Orleans Saints during the second half at GEHA Field at Arrowhead Stadium. Mandatory Credit: Denny Medley-Imagn Images

On Sunday afternoon, Levi’s Stadium will witness an exciting NFL Week 7 matchup between the Kansas City Chiefs and the San Francisco 49ers. The Kansas City Chiefs are undefeated at the top of the AFC West with a 5-0 record. The San Francisco 49ers are also grinning in the first position of the NFC West with an even 3-3 current record. According to the latest NFL betting odds, the San Francisco 49ers will win this matchup.


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The preview information

Date: October 20, Sunday | Time: 4:25 p.m. Eastern Time

Location: Levi’s Stadium, Santa Clara, California

TV: FOX

Stream: NFL+/Fubo TV

Kansas City Chiefs Vs San Francisco 49ers Odds, Spread, Moneyline

Moneyline: Kansas City Chiefs (+100) vs San Francisco 49ers (-120)

Spread: Kansas City Chiefs +1.5 (-110) vs San Francisco 49ers -1.5 (-110)

Total (O/U): Kansas City Chiefs (u46.5) vs San Francisco 49ers (o46.5)

Kansas City Chiefs

The Kansas City Chiefs took on the New Orleans Saints in NFL Week 6 and won the game with a final score of 26-13. Against the Saints, Kansas City’s QB Patrick Mahomes went for 331 yards, completing 28 passes out of 39 with a single interception. Kareem Hunt managed 27 carries for 102 yards in rushing, with a solo score. On defense, JuJu Smith-Schuster contributed seven receptions for 130 yards in that game.

Top 3 Players

Patrick Mahomes: 1,235 Yds, 6 TD, 6 INT

Kareem Hunt: 41 Car, 171 Yds, 1 TD

Rashee Rice: 24 Rec, 288 Yds, 2 TD

San Francisco 49ers

The San Francisco 49ers are coming here after winning against the Seattle Seahawks last time out with a final score of 36-24. In that game, San Francisco’s QB Brock Purdy scored 255 yards, completing 18 passes out of 28. The QB managed to score three TDs for the team against the Seahawks. Isaac Guerendo took charge of the rushing with ten carries for 99 yards, while Deebo Samuel Sr. managed three receptions and a single TD on defense.

Top 3 Players

Brock Purdy: 1,629 Yds, 9 TD, 4 INT

Jordan Mason: 114 Car, 609 Yds, 3 TD

Jauan Jennings: 25 Rec, 404 Yds, 3 TD

Kansas City Chiefs Vs San Francisco 49ers Injury Report

Kansas City Chiefs

Marquise Brown (WR) IR, Shoulder

Isaih Pacheco (RB) IR, Fibula

Rashee Rice (WR) IR; is out for season, Knee

McKade Mettauer (G) IR, Knee

San Francisco 49ers

Javon Hargrave (NT) Is out for season, Triceps

Jon Feliciano (G) IR, Undisclosed

Christian McCaffrey (RB) IR, Calf

Charvarius Ward (CB) Is “?” Sunday vs Kansas City, Knee

Matthew Wright (K) Is “?” Sunday vs Kansas City, Shoulder

Demetrius Flannigan-Fowles (LB) Is “?” Sunday vs Kansas City, Calf

Jordan Elliott (DT) Is “?” Sunday vs Kansas City, Knee

Yetur Gross-Matos (DE) IR, Knee

Ambry Thomas (CB) IR, Undisclosed

Talanoa Hufanga (S) IR, Wrist

Eli Mitchell (RB) IR, Hamstring

Curtis Robinson (LB) Is out for season, ACL

Jordan Mason (RB) Is “?” Sunday vs Kansas City, Shoulder

Jake Moody (K) Is out indefinitely, Ankle

Malik Mustapha (S) Is “?” Sunday vs Kansas City, Ankle

Kansas City Chiefs Vs San Francisco 49ers Betting Trends

Kansas City Chiefs

Kansas City are 9-1-1 ATS in their last 11 games.

The total has gone UNDER in 8 of Kansas City’s last 12 games.

Kansas City are 10-0 SU in their last 10 games.

Kansas City are 7-1 ATS in their last 8 games against San Francisco.

Kansas City are 6-1 SU in their last 7 games against San Francisco.

Kansas City are 6-0 SU in their last 6 games on the road.

Kansas City are 1-5 SU in their last 6 games when playing on the road against San Francisco.

Kansas City are 12-3 ATS in their last 15 games against an opponent in the National Football Conference.

Kansas City are 6-0 ATS in their last 6 games against an opponent in the National Football Conference West division.

The total has gone UNDER in 5 of Kansas City’s last 5 games played in October.

San Francisco 49ers

San Francisco are 3-7 ATS in their last 10 games.

The total has gone OVER in 6 of San Francisco’s last 8 games.

San Francisco are 12-6 SU in their last 18 games.

The total has gone OVER in 5 of San Francisco’s last 7 games against Kansas City.

San Francisco are 2-8 ATS in their last 10 games at home.

San Francisco are 5-1 SU in their last 6 games when playing at home against Kansas City.

The total has gone OVER in 5 of San Francisco’s last 6 games against an opponent in the American Football Conference.

San Francisco are 0-6 ATS in their last 6 games against an opponent in the American Football Conference West division.

San Francisco are 1-4 SU in their last 5 games played in October.

The total has gone UNDER in 4 of San Francisco’s last 6 games played in week 7.

Kansas City Chiefs Vs San Francisco 49ers Summary and Prediction

The Kansas City Chiefs are doing too well at the moment, and will try to take advantage of San Francisco’s many injuries. Kansas City’s unbeaten record seems to be coming to an end here. Take the San Francisco 49ers to win 27-19.

Moneyline: 49ers (-120)

Spread: Under 1.5

Total: Over 46.5

Predicted Score: 27-19, 49ers win.



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This article first appeared on Gridiron Heroics and was syndicated with permission.

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