Los Angeles Chargers vs. Arizona Cardinals Prediction, Odds, Moneyline 10/21/2024

The preview information

Date: October 21, Monday | Time: 9:00 p.m. Eastern Time

Location: State Farm Stadium, Glendale, Arizona

TV: ESPN+

Stream: NFL+/Fubo TV

*All odds are subject to change depending on the time of this posting

Los Angeles Chargers Vs Arizona Cardinals Odds, Spread, Moneyline

Moneyline: Los Angeles Chargers (-145) vs Arizona Cardinals (+125)

Spread: Los Angeles Chargers -2.5 (-120) vs Arizona Cardinals +2.5 (+100)

Total (O/U): Los Angeles Chargers (u43.5) vs Arizona Cardinals (o43.5)

*All odds are subject to change depending on the time of this posting

Los Angeles Chargers

The Los Angeles Chargers played the Denver Broncos before coming here and won the game with a final score of 23-16. In that game, LA’s QB Justin Herbert went for 237 yards, completing 21 passes out of 34 along with a single score. In rushing, J.K. Dobbins led the team with 25 carries for 96 yards, scoring a single TD. On defense, Simi Fehoko contributed two receptions for 44 yards in that game.

Top 3 Players

Justin Herbert: 815 Yds, 6 TD, 1 INT

J.K. Dobbins: 81 Car, 438 Yds, 3 TD

Ladd McConkey: 19 Rec, 219 Yds, 2 TD

Arizona Cardinals

The Arizona Cardinals took on the Green Bay Packers in NFL Week 6 and lost the game with a disappointing score of 34-13. Against the Packers, Arizona’s Kyler Murray went for 214 yards, completing 22 passes out of 32, and scoring once. Trey Benson took charge of the rushing with five carries for 26 yards. In terms of defense, the Cardinals had Trey McBride contributing eight receptions for 96 yards.

Top 3 Players

Kyler Murray: 1,186 Yds, 8 TD, 2 INT

James Conner: 90 Car, 403 Yds, 3 TD

Marvin Harrison Jr.: 17 Rec, 279 Yds, 4 TD

Los Angeles Chargers Vs Arizona Cardinals Injury Report

Los Angeles Chargers

Joey Bosa (DE) Is “?” Monday vs Arizona, Hip

Hayden Hurst (TE) Left last game, is “?” Monday vs Arizona, Groin

Gus Edwards (RB) IR, Ankle

Asante Samuel Jr. (CB) IR, Shoulder

Chris Rumph II (LB) IR, Foot

Deane Leonard (CB) Left last game, is “?” Monday vs Arizona, Hamstring

Ja’Sir Taylor (CB) Is “?” Monday vs Arizona, Undisclosed

Quentin Johnston (WR) Left last game, is “?” Monday vs Arizona, Ankle

Ladd McConkey (WR) Is “?” to return, Concussion

Tyler McLellan (T) IR, Undisclosed

Bucky Williams (C) IR, Undisclosed

Chris Collins (LB) IR, Undisclosed

Arizona Cardinals

Matt Prater (K) Is “?” Monday vs LA Chargers, Knee

Zay Jones (WR) Is “?” Monday vs LA Chargers, Hamstring

Will Hernandez (G) IR, Knee

Justin Jones (DT) IR, Triceps

Bilal Nichols (DT) Left last game, is “?” Monday vs LA Chargers, Stinger

Kyzir White (LB) Left last game, is “?” Monday vs LA Chargers, Knee

Evan Brown (C) Left last game, is “?” Monday vs LA Chargers, Ankle

Sean Murphy-Bunting (CB) Left last game, is “?” Monday vs LA Chargers, Neck

Joey Blount (S) Left last game, is “?” Monday vs LA Chargers, Hamstring

BJ Ojulari (LB) IR, Knee

Marvin Harrison Jr. (WR) Left last game, is “?” Monday vs LA Chargers, Concussion

Darius Robinson (DT) IR, Calf

Elijah Jones (CB) IR, Ankle

Los Angeles Chargers Vs Arizona Cardinals Betting Trends

Los Angeles Chargers

The total has gone UNDER in 6 of LA Chargers’ last 7 games.

The LA Chargers are 4-10 SU in their last 14 games.

LA Chargers are 4-2 ATS in their last 6 games against Arizona.

The LA Chargers are 5-1 SU in their last 6 games against Arizona.

The total has gone UNDER in 8 of LA Chargers’ last 10 games on the road.

LA Chargers are 5-1 ATS in their last 6 games when playing on the road against Arizona.

The total has gone UNDER in 5 of LA Chargers’ last 6 games against an opponent in the National Football Conference.

LA Chargers are 8-3 SU in their last 11 games against an opponent in the National Football Conference West division.

The LA Chargers are 6-3 SU in their last 9 games played in October.

Arizona Cardinals

Arizona are 5-15 SU in their last 20 games.

Arizona are 1-5 SU in their last 6 games at home.

Arizona are 1-5 ATS in their last 6 games when playing at home against the LA Chargers.

Arizona are 1-8 SU in their last 9 games against an opponent in the American Football Conference.

The total has gone OVER in 4 of Arizona’s last 6 games against an opponent in the American Football Conference West division.

Arizona are 2-6 ATS in their last 8 games played in October.

The total has gone UNDER in 7 of Arizona’s last 10 games played in week 7.

Los Angeles Chargers Vs Arizona Cardinals Summary and Prediction

The Los Angeles Chargers have put on insipid performances this season, and this is not likely to change here. The Cardinals are easily the better team on both ends in this pairing. As per the top NFL Week 7 betting picks, the Arizona Cardinals will win 25-19.

Moneyline: Cardinals (+125)

Spread: Over 2.5

Total: Over 43.5

Predicted Score: 25-19, Cardinals win.